Radiomics: A Well-Intentioned Leap of Faith

RESTORE--from deduction to leap of faith.

inhibition of pacemaker output in pacemaker-dependent patients and/or false triggering with tracking to the upper rate limit in patients with reduced left ventricular function may be detrimental. Therefore, we cannot support the approach of Martin and co-workers—that is, to leave the pacemaker sensing function activated. In contrast, we recommend deactivating the sensing function in pacemaker-d...

A global health fund: a leap of faith?

Leptin and the obesity hypoventilation syndrome: a leap of faith?

he discovery of the anti-obesity hormone leptin (the name is derived from the Greek " leptos " meaning " thin "), the product of the ob gene, 1 has fuelled a recent surge of interest in the mechanisms regulating mammalian fat stores. Leptin, a 16 kD protein of 167 amino acids with a similar crystal structure to cytokines, 2 is produced primarily by white adipose tissue. 3 The hormone elicits ap...

Making mandatory vaccination truly compulsory: well intentioned but ill conceived.

872 www.thelancet.com/infection Vol 15 August 2015 3 WHO. Fifty-fourth World Health Assembly. WHA54.19. Schistosomiasis and soil-transmitted helminth infections. May, 22, 2001. http://apps.who. int/gb/archive/pdf_fi les/WHA54/ea54r19.pdf (accessed March 23, 2015). 4 Uniting to Combat Neglected Tropical Diseases. London Declaration on Neglected Tropical Diseases. http://www.who.int/neglected_dis...

National Dementia Strategy: well intentioned--but how well founded and how well directed?

The National Dementia Strategy was published in February 2009. It was eagerly anticipated and has generated a good deal of sustained media interest, widened awareness, and heightened expectation of better help for people with dementia. The three ambitions of the strategy--to raise awareness, facilitate assessment, and improve services--are unquestionably correct; but the assumptions, emphases, ...